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Article

Polyphyletic strains of hepatitis E virus are responsible for sporadic cases of acute hepatitis in Japan.

Journal of clinical microbiology - 1 Sept 2002

Mizuo Hitoshi, Suzuki Kazuyuki, Takikawa Yasuhiro, Sugai Yoshiki, Tokita Hajime, Akahane Yoshihiro, Itoh Keiichi, Gotanda Yuhko, Takahashi Masaharu, Nishizawa Tsutomu, Okamoto Hiroaki

Abstract excerpt

Among 87 patients who were previously treated for acute hepatitis of unknown etiology between 1992 and 2001 at five hospitals in Japan, 11 (13%) patients were positive for immunoglobulin M-class antibodies to hepatitis E virus (HEV) by enzyme immunoassay and had detectable HEV RNA by reverse transcription-PCR with two independent sets of primers derived from well-conserved genomic areas in open reading frames 1...

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Identifiers

PMID: 12202555
DOI: 10.1128/JCM.40.9.3209-3218.2002
PMCID: PMC130758

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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