Article
Genetic heterogeneity of hepatitis E virus recovered from Japanese patients with acute sporadic hepatitis.
The Journal of infectious diseases - 1 May 2002
Takahashi Kazuaki, Kang Jong-Hon, Ohnishi Sachiyo, Hino Kunihiko, Mishiro Shunji
Abstract excerpt
The recent discovery of a presumably Japan-indigenous hepatitis E virus (HEV) strain (JRA1) spurred analysis of additional isolates from 7 cases of acute sporadic hepatitis E infection. Comparison of a 326-nucleotide region from open-reading frame 1 indicated that 1, 3, and 3 isolates segregated to genotypes I, III, and IV, respectively. Six patients had not traveled abroad recently. One patient had traveled to...
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