Article
Leukocyte-endothelial cell adhesion molecule 1 (LECAM-1) polymorphism is associated with diabetic nephropathy in type 2 diabetes mellitus.
Journal of diabetes and its complications - 1 Jan 2000
Kamiuchi Kenji, Hasegawa Goji, Obayashi Hiroshi, Kitamura Akane, Ishii Michiyo, Yano Miho, Kanatsuna Takahiro, Yoshikawa Toshikazu, Nakamura Naoto
Abstract excerpt
BACKGROUND/AIMS: Glomerular infiltration with monocytes/macrophages has been implicated in the pathogenesis of diabetic nephropathy. In this study, we evaluated the relationship between the genetic polymorphism in leukocyte-endothelial adhesion molecule-1 (LECAM-1) and diabetic nephropathy in patients with type 2 diabetes mellitus. METHODS: We determined the frequency of the LECAM-1 P213S genotype in 102 diabetic...
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