Article
Minisatellite and HPRT mutations in V79 and human cells irradiated with gamma rays.
Radiation protection dosimetry - 1 Jan 2002
Canova S, Perin M, Mognato M, Favaretto S, Cherubini R, Celotti L
Abstract excerpt
The induction of mutations at the Hprt locus and minisatellite sequences was studied in V79 cells, peripheral blood lymphocytes (PBL) and lymphoblastoid cells (CCRF-CEM) exposed to gamma rays. In V79 cells the Hprt mutant frequency increased with dose at least up to 6.0 Gy, whereas the number of HPRT mutant lymphocytes increased up to 3 Gy. Clones derived from single irradiated cells were screened for mutations...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
