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Article

Meiotic Arrest in the Mouse Follicle Maintained by a G <sub>s</sub> Protein in the Oocyte

23 Aug 2002

Abstract excerpt

The mammalian ovarian follicle consists of a multilayered complex of somatic cells that surround the oocyte. A signal from the follicle cells keeps the oocyte cell cycle arrested at prophase of meiosis I until luteinizing hormone from the pituitary acts on the follicle cells to release the arrest, causing meiosis to continue. Here we show that meiotic arrest can be released in mice by microinjecting the oocyte...

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Identifiers

PMID: 12193786
DOI: 10.1126/science.1073978

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Related research

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Research trail→

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Meiotic Arrest in the Mouse Follicle Maintained by a G <sub>s</sub> Protein in the OocytePMID 12193786Read ↗

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