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Article

Detection of viral infection and gene expression in clinical tissue specimens using branched DNA (bDNA) in situ hybridization.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Sept 2002

Kenny Daryn, Shen Lu-Ping, Kolberg Janice A

Abstract excerpt

In situ hybridization (ISH) methods for detection of nucleic acid sequences have proved especially powerful for revealing genetic markers and gene expression in a morphological context. Although target and signal amplification technologies have enabled researchers to detect relatively low-abundance molecules in cell extracts, the sensitive detection of nucleic acid sequences in tissue specimens has proved more...

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Identifiers

PMID: 12185200
DOI: 10.1177/002215540205000909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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