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Article

Neuropathologic and clinical features in eight Chinese patients with Leigh disease.

Journal of child neurology - 1 Jun 2002

Jiang Yu-Wu, Qin Jiong, Yuan Yun, Qi Yu, Wu Xi-Ru

Abstract excerpt

We present the neuropathologic and clinical features of eight Chinese patients with Leigh disease. Five cases had onset before 1 year of age, the other three after 1 year of age. Cranial magnetic resonance imaging (MRI) demonstrated symmetric and bilateral long T1 and long T2 lesions mainly in the basal ganglia and brain stem. The putamen was most commonly and severely affected. Brain neuropathologic examinations...

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PMID: 12174968
DOI: 10.1177/088307380201700611

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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