Article
The genetics of alcoholism in Polynesians: alcohol and aldehyde dehydrogenase genotypes in young men.
Alcoholism, clinical and experimental research - 1 Jul 2002
Chambers Geoffrey K, Marshall Stephen J, Robinson Geoffrey M, Maguire Sean, Newton-Howes Jan, Chong Nicola L
Abstract excerpt
BACKGROUND: The last 10 years have seen growing recognition of the significance of the genes encoding enzymes responsible for hepatic alcohol metabolism as protective factors in the development of alcoholism. METHODS: We have developed DNA sequencing assays for measuring genetic variation at the alcohol dehydrogenase 2 (ADH2), ADH3, and aldehyde dehydrogenase 2 (ALDH2) loci. These have been used to survey...
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