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Molecular Analysis of Three Ljungan Virus Isolates Reveals a New, Close-to-Root Lineage of the <i>Picornaviridae</i> with a Cluster of Two Unrelated 2A Proteins

1 Sept 2002

Abstract excerpt

Ljungan virus (LV) is a suspected human pathogen recently isolated from bank voles (Clethrionomys glareolus). In the present study, it is revealed through comparative sequence analysis that three newly determined Swedish LV genomes are closely related and possess a deviant picornavirus-like organization: 5' untranslated region-VP0-VP3-VP1-2A1-2A2-2B-2C-3A-3B-3C-3D-3' untranslated region. The LV genomes and the...

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PMID: 12163611
DOI: 10.1128/jvi.76.17.8920-8930.2002

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