Article
Ductal carcinoma in situ of the breast: a new phenotype classification system and its relation to prognosis.
Breast cancer research and treatment - 1 Jun 2002
Wärnberg F, Casalini P, Nordgren H, Bergkvist L, Holmberg L, Ménard S
Abstract excerpt
In a study of invasive breast cancer, multiple correspondence analysis (MCA) revealed clustering of eight pathobiological variables. Two different phenotypes were distinguished by an index calculated on the basis of the variables (histologic grade, necrosis, lymphoid infiltration, number of mitosis and expression of c-erbB-2, p53, progesterone receptor and Bcl-2). Phenotype A lesions share most of the features of...
Topics
- Adult
- Aged
- Breast Neoplasms
- Carcinoma, Intraductal, Noninfiltrating
- Cohort Studies
- Disease Progression
- Female
- Gene Expression Regulation, Neoplastic
- Humans
- Mammography
- Middle Aged
