Article
Characterization of soluble CD40 ligand released from human activated platelets.
Journal of medical and dental sciences - 1 Mar 2001
Jin Y, Nonoyama S, Morio T, Imai K, Ochs H D, Mizutani S
Abstract excerpt
We report here that soluble CD40 ligand (sCD40L) is released from human platelets when activated with collagen or thrombin. The sCD40L was detectable in the culture supernatants of platelets within 30 min after stimulation in vitro, and reached maximal levels in 3 h. The release was blocked by th...
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