Article
From Zebrafish to human: modular medical models.
Annual review of genomics and human genetics - 1 Jan 2002
Shin Jordan T, Fishman Mark C
Abstract excerpt
Genetic screens in Drosophila melanogaster, Caenorhabditis elegans, and Danio rerio clarified the logic of metazoan development by revealing critical unitary steps and pathways to embryogenesis. Can genetic screens similarly organize medicine? We here examine human diseases that resemble mutations in Danio rerio, the zebrafish, the one vertebrate species for which large-scale genetic screens have been performed...
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