Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TYRP1 and MC1R genotypes and their effects on coat color in dogs.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Jul 2002

Schmutz Sheila M, Berryere Tom G, Goldfinch Angela D

Abstract excerpt

We used PCR amplification of cDNA prepared from skin biopsies to determine the nearly full-length, protein-coding sequence of dog TYRP1, and to define sequence variants potentially responsible for the B locus. One common variant contained a premature stop codon in exon 5 (Q331ter), and the other deleted a proline residue in exon 5 (345delP). A third variant in exon 2 (S41C) occurred less frequently. We genotyped...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dogs
Share to Hair Color
Share to Membrane Glycoproteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Nasal Mucosa

Share to Oxidoreductases

Share to Receptors, Corticotropin

Share to Receptors, Melanocortin

Source

Identifiers

PMID: 12140685
DOI: 10.1007/s00335-001-2147-2

Genes

TYRP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TYRP1 and MC1R genotypes and their effects on coat color in dogs.PMID 12140685Read ↗

Chocolate coated cats: TYRP1 mutations for brown color in domestic cats.Semantic proximity Read ↗

Two brown coat colour-associated TYRP1 variants (bc and bd ) occur in Leonberger dogs.Semantic proximity Read ↗

Tyrosinase and tyrosinase related protein 1 alleles specify domestic cat coat color phenotypes of the albino and brown loci.Semantic proximity Read ↗

Sequence characterization of the MC1R gene in yak (Poephagus grunniens) breeds with different coat colors.Semantic proximity Read ↗

Two MC1R loss-of-function alleles in cream-coloured Australian Cattle Dogs and white Huskies.Semantic proximity Read ↗

Genes affecting coat colour and pattern in domestic dogs: a review.Semantic proximity Read ↗

Compelling evidence that a single nucleotide substitution in TYRP1 is responsible for coat-colour polymorphism in a free-living population of Soay sheep.Semantic proximity Read ↗

The b(c) allele of TYRP1 is causative for the recessive brown (liver) colour in German Shepherd dogs.Semantic proximity Read ↗

Coat color DNA testing in dogs: theory meets practice.Semantic proximity Read ↗

MC1R c.310G>- and c.871G > A determine the coat color of Kumamoto sub-breed of Japanese Brown cattle.Semantic proximity Read ↗

The genetics of brown coat color and white spotting in domestic yaks (Bos grunniens).Semantic proximity Read ↗

Melanocortin-1 receptor mutations and pigmentation: Insights from large animals.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.