Article
Compelling evidence that a single nucleotide substitution in TYRP1 is responsible for coat-colour polymorphism in a free-living population of Soay sheep.
Proceedings. Biological sciences - 7 Mar 2007
Gratten J, Beraldi D, Lowder B V, McRae A F, Visscher P M, Pemberton J M, Slate J
Abstract excerpt
Identifying the genes that underlie phenotypic variation in natural populations is a central objective of evolutionary genetics. Here, we report the identification of the gene and causal mutation underlying coat colour variation in a free-living population of Soay sheep (Ovis aries). We targeted tyrosinase-related protein 1 (TYRP1), a positional candidate gene based on previous work that mapped the Coat colour...
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