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Article

Tyrosinase and tyrosinase related protein 1 alleles specify domestic cat coat color phenotypes of the albino and brown loci.

The Journal of heredity - 1 Jan 2000

Schmidt-Küntzel A, Eizirik E, O'Brien S J, Menotti-Raymond M

Abstract excerpt

The genes encoding enzymes of the tyrosinase family are strong candidates for coat color variation in mammals. To investigate their influence in domestic cat coat color, we determined the complete nucleotide coding sequence of the domestic cat genes tyrosinase (TYR)--a plausible candidate gene for the albino (C) locus, and tyrosinase related protein 1 (TYRP1)--a candidate gene for the brown (B) locus. Sequence...

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Source

Identifiers

PMID: 15858157
DOI: 10.1093/jhered/esi066

Genes

TYRP1
TYR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

Tyrosinase and tyrosinase related protein 1 alleles specify domestic cat coat color phenotypes of the albino and brown loci.PMID 15858157Read ↗

Chocolate coated cats: TYRP1 mutations for brown color in domestic cats.Semantic proximity Read ↗

Albinism in the domestic cat (Felis catus) is associated with a tyrosinase (TYR) mutation.Semantic proximity Read ↗

Compelling evidence that a single nucleotide substitution in TYRP1 is responsible for coat-colour polymorphism in a free-living population of Soay sheep.Semantic proximity Read ↗

A premature stop codon in the TYRP1 gene is associated with brown coat colour in the European rabbit (Oryctolagus cuniculus).Semantic proximity Read ↗

Identification of TYR gene variants associated with white coat color in Hanwoo cattle using whole-genome sequencing.Semantic proximity Read ↗

Tyrosinase mutations associated with Siamese and Burmese patterns in the domestic cat (Felis catus).Semantic proximity Read ↗

TYRP1 is associated with dun coat colour in Dexter cattle or how now brown cow?Semantic proximity Read ↗

Molecular cloning, sequence characteristics, and polymorphism analyses of the tyrosinase-related protein 2 / DOPAchrome tautomerase gene of black-boned sheep (Ovis aries).Semantic proximity Read ↗

TYRP1 and MC1R genotypes and their effects on coat color in dogs.Semantic proximity Read ↗

The albinism of the feral Asinara white donkeys (Equus asinus) is determined by a missense mutation in a highly conserved position of the tyrosinase (TYR) gene deduced protein.Semantic proximity Read ↗

A genome-wide scan study identifies a single nucleotide substitution in ASIP associated with white versus non-white coat-colour variation in sheep (Ovis aries).Semantic proximity Read ↗

The brown coat colour of Coppernecked goats is associated with a non-synonymous variant at the TYRP1 locus on chromosome 8.Semantic proximity Read ↗

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