Article
Evidence for a genetic association between monoamine oxidase A and restless legs syndrome.
Neurology - 23 Jul 2002
Desautels A, Turecki G, Montplaisir J, Brisebois K, Sequeira A, Adam B, Rouleau G A
Abstract excerpt
BACKGROUND: Impairment in the central dopaminergic system has been consistently suggested as an etiologic factor in restless legs syndrome (RLS). OBJECTIVE: To investigate a possible role for the MAOA and MAOB genes in RLS using a population-based association study. METHODS: In addition to a dinucleotide repeat located within the second intron of the MAOB gene, a functional variable number of tandem repeat (VNTR)...
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