Article
Prediction of drug resistance in M. tuberculosis: molecular mechanisms, tools, and applications.
IUBMB life - 1 Jan 2000
Victor Thomas C, van Helden Paul D, Warren Robin
Abstract excerpt
Management of Tuberculosis is complicated by the emergence of drug resistant strains of Mycobacterium tuberculosis and this poses a threat to the success of Tuberculosis control programmes. Drug susceptibility testing by culture is time-consuming and technically difficult. It is known that resistance to drugs is due to a number of genomic mutations in specific genes of M. tuberculosis. These mutations in...
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