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Article

Prevalence of HIV-1 polymerase gene mutations in pre-treated patients in Thailand.

The Southeast Asian journal of tropical medicine and public health - 1 Mar 2002

Chantratita Wasun, Jenwitheesuk Ekachai, Watitpun Chotip, Pongthanapisith Viroj, Vibhagool Asda, Leechawengwong Manoon, Sookpranee Mondej, Apairatana Anantasak

Abstract excerpt

To determine the prevalence of drug resistance-conferring mutations in human immunodeficiency virus type 1 (HIV-1), 83 HIV-1 infected Thai patients who had been treated with any antiretroviral drug were studied. HIV-1 RNA was reverse transcribed and amplified by RT-PCR. The direct sequencing of HIV-1 reverse transcriptase (RT) and protease was then performed. Changes in nucleotide and amino acid sequences were...

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PMID: 12118466

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