Article
HPV16 and HPV18 in genital tumors: Significantly different levels of viral integration and correlation to tumor invasiveness
2 Jul 2002
Abstract excerpt
The integration of the high-risk HPV16 and HPV18 types into the cell genome is considered an important step in malignant transformation. The relationship between the physical status of the virus and clinical/pathological parameters was studied by type-specific and multiplex PCR for E6, E2, and E1 sequences in 86 genital tumors from different sites, consisting of 69 invasive carcinomas (including 5 microinvasive...
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