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Article

The effect of anti-CD40 ligand antibody on B cells in human systemic lupus erythematosus.

Arthritis and rheumatism - 1 Jun 2002

Huang Weiqing, Sinha Jayashree, Newman Jeffrey, Reddy Bhoompally, Budhai Lalbachan, Furie Richard, Vaishnaw Akshay, Davidson Anne

Abstract excerpt

OBJECTIVE: To determine the immunologic effects of anti-CD40 ligand (anti-CD40L) therapy in 5 patients with systemic lupus erythematosus nephritis who participated in an open-label study of a humanized anti-CD40L monoclonal antibody. METHODS: Serum and peripheral blood mononuclear cells were obtained before, during, and after treatment, and the frequency of Ig and anti-DNA antibody-secreting B cells was analyzed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12115186
DOI: 10.1002/art.10273

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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