Article
Two-dimensional electrophoresis analysis of the extracellular proteome of Bacillus cereus reveals the importance of the PlcR regulon.
Proteomics - 1 Jun 2002
Gohar Michel, Økstad Ole Andreas, Gilois Nathalie, Sanchis Vincent, Kolstø Anne-Brit, Lereclus Didier
Abstract excerpt
Many virulence factors are secreted by the gram-positive, spore forming bacterium Bacillus cereus. Most of them are regulated by the transcriptional activator, PlcR, which is maximally expressed at the beginning of the stationary phase. We used a proteomic approach to study the impact of the PlcR regulon on the secreted proteins of B. cereus, by comparing the extracellular proteomes of strains ATCC 14579 and ATCC...
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