Article
Isolation and sequencing of a novel tropomyosin isoform preferentially associated with colon cancer.
Gastroenterology - 1 Jul 2002
Lin Jenny L-C, Geng Xin, Bhattacharya Sangeeta Das, Yu Jae-Ran, Reiter Rebecca S, Sastri Bhagyalakshmi, Glazier Kenneth D, Mirza Zafar K, Wang Kenneth K, Amenta Peter S, Das Kiron M, Lin Jim J-C
Abstract excerpt
BACKGROUND & AIMS: Nonmuscle human tropomyosin (hTM) isoforms have distinct functions and may play important roles in various disease processes. METHODS: In an attempt to identify colon epithelial tropomyosin isoform, a complementary DNA library prepared from a human colon cancer cell line T84 was screened by an oligonucleotide probe complementary to messages of all known hTM isoforms. A novel clone called TC22...
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