Article
Use of the random amplified polymorphic DNA (RAPD) assay for the detection of DNA damage and mutations: possible implications of confounding factors.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Jan 2000
Atienzar Franck A, Evenden Andrew J, Jha Awadhesh N, Depledge Michael H
Abstract excerpt
The aim of this study was to evaluate the potential of the random amplified polymorphic DNA (RAPD) assay to qualitatively detect the kinetics of benzo[a]pyrene (B[a]P)-induced DNA effects in the water flea Daphnia magna exposed to 25 and 50 micrograms l-1 B[a]P for 7 and 6 days, respectively. Mortality was recorded on a daily basis in both experiments, and RAPD analysis was performed on samples collected every...
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