Article
Probing the importance and potential roles of the binding of the PH-domain protein Boi1 to acidic phospholipids.
BMC cell biology - 27 Jun 2002
Hallett Mark A, Lo H Shuen, Bender Alan
Abstract excerpt
BACKGROUND: The related proteins Boi1 and Boi2, which appear to promote polarized growth in S. cerevisiae, both contain a PH (pleckstrin homology) and an SH3 (src homology 3) domain. Previously, we gained evidence that a PH domain-bearing segment of Boi1, which we call Boi1-PH, is sufficient and necessary for function. In the current study, we investigate the binding of Boi1's PH domain to the acidic...
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