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Article

Clostridium difficile genotyping based on slpA variable region in S-layer gene sequence: an alternative to serotyping.

Journal of clinical microbiology - 1 Jul 2002

Karjalainen Tuomo, Saumier Nicolas, Barc Marie-Claude, Delmée Michel, Collignon Anne

Abstract excerpt

Recent investigations of Clostridium difficile cell wall components have revealed the presence of an S-layer encoded by the slpA gene. The aim of this study was to determine whether slpA genotyping can be used as an alternative to serotyping. The variable regions of slpA were amplified by PCR from serogroup reference strains and various clinical isolates chosen randomly. Amplified products were analyzed after...

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Source

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Identifiers

PMID: 12089261
DOI: 10.1128/JCM.40.7.2452-2458.2002
PMCID: PMC120536

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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