Article
Serotonin transporter gene polymorphism and myocardial infarction: Etude Cas-Témoins de l'Infarctus du Myocarde (ECTIM).
Circulation - 25 Jun 2002
Fumeron Frédéric, Betoulle Dina, Nicaud Viviane, Evans Alun, Kee Frank, Ruidavets Jean-Bernard, Arveiler Dominique, Luc Gérald, Cambien François
Abstract excerpt
BACKGROUND: Depression is a risk factor for myocardial infarction (MI). Selective serotonin reuptake inhibitors reduce this risk. The site of action is the serotonin transporter (SLC6A4), which is expressed in brain and blood cells. A functional polymorphism in the promoter region of the SLC6A4 gene has been described. This polymorphism may be associated with the risk of MI. METHODS AND RESULTS: The SLC6A4...
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