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Article

Mutations in the helix 3 region of the androgen receptor abrogate ARA70 promotion of 17beta-estradiol-induced androgen receptor transactivation.

The Journal of biological chemistry - 27 Sept 2002

Thin Tin Htwe, Kim Eungseok, Yeh Shuyuan, Sampson Erik R, Chen Yei-Tsung, Collins Loretta L, Basavappa Ravi, Chang Chawnshang

Abstract excerpt

The influence of estrogen on the development of the male reproductive system may be interrupted in a subset of partial androgen insensitivity syndrome (PAIS) patients. PAIS describes a wide range of male undermasculinization resulting from mutations in the androgen receptor (AR) or steroid metabolism enzymes that perturb androgen-AR regulation of male sex organ development. In this study, we are interested in...

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PMID: 12068007
DOI: 10.1074/jbc.M202824200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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