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Article

Identification of genes periodically expressed in the human cell cycle and their expression in tumors.

Molecular biology of the cell - 1 Jun 2002

Whitfield Michael L, Sherlock Gavin, Saldanha Alok J, Murray John I, Ball Catherine A, Alexander Karen E, Matese John C, Perou Charles M, Hurt Myra M, Brown Patrick O, Botstein David

Abstract excerpt

The genome-wide program of gene expression during the cell division cycle in a human cancer cell line (HeLa) was characterized using cDNA microarrays. Transcripts of >850 genes showed periodic variation during the cell cycle. Hierarchical clustering of the expression patterns revealed coexpressed groups of previously well-characterized genes involved in essential cell cycle processes such as DNA replication,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 12058064
DOI: 10.1091/mbc.02-02-0030
PMCID: PMC117619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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