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Article

Toxic waste disposal in Escherichia coli.

Journal of bacteriology - 1 Jul 2002

Helling Robert B, Janes Brian K, Kimball Heather, Tran Timothy, Bundesmann Michael, Check Pietra, Phelan Darcy, Miller Charles

Abstract excerpt

About 10% of the nalidixic acid-resistant (Nal(r)) mutants in a transposition-induced library exhibited a growth factor requirement as the result of cysH, icdA, metE, or purB mutation. Resistance in all of these mutants required a functional AcrAB-TolC efflux pump, but the EmrAB-TolC pump played no obvious role. Transcription of acrAB was increased in each type of Nal(r) mutant. In the icdA and purB mutants, each...

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Identifiers

PMID: 12057966
DOI: 10.1128/JB.184.13.3699-3703.2002
PMCID: PMC135154

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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