Article
Principles, organization, and operation of a DNA bank for clinical trials: a Department of Veterans Affairs cooperative study.
Controlled clinical trials - 1 Jun 2002
Lavori Philip W, Krause-Steinrauf Heidi, Brophy Mary, Buxbaum Joel, Cockroft Jennifer, Cox David R, Fiore Louis, Greely Henry T, Greenberg Harry, Holmes Edward W, Nelson Lorene M, Sugarman Jeremy
Abstract excerpt
The mapping and sequencing of the human genome promises rapid growth in understanding the genetically influenced mechanisms that underlie human disease. To realize this promise fully, it is necessary to relate genetic information to clinical phenotypes. Genetic tissue banking in clinical studies provides opportunities to analyze the genetic contribution to variation in response to treatments. The challenges to...
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