Article
Norwalk virus binds to histo-blood group antigens present on gastroduodenal epithelial cells of secretor individuals.
Gastroenterology - 1 Jun 2002
Marionneau Severine, Ruvoën Nathalie, Le Moullac-Vaidye Beatrice, Clement Monique, Cailleau-Thomas Anne, Ruiz-Palacois Guillermo, Huang Pengwei, Jiang Xi, Le Pendu Jacques
Abstract excerpt
BACKGROUND & AIMS: Norwalk Virus (NV) is a member of the Caliciviridae family, which causes acute epidemic gastroenteritis in humans of all ages and its cellular receptors have not yet been characterized. Another calicivirus, Rabbit Hemorrhagic Disease Virus, attaches to H type 2 histo-blood group oligosaccharide present on rabbit epithelial cells. Our aim was to test if, by analogy, recombinant NV-like particles...
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