Article
Histo-blood group antigens act as attachment factors of rabbit hemorrhagic disease virus infection in a virus strain-dependent manner.
PLoS pathogens - 1 Aug 2011
Nyström Kristina, Le Gall-Reculé Ghislaine, Grassi Paola, Abrantes Joana, Ruvoën-Clouet Nathalie, Le Moullac-Vaidye Beatrice, Lopes Ana M, Esteves Pedro J, Strive Tanja, Marchandeau Stéphane, Dell Anne, Haslam Stuart M, Le Pendu Jacques
Abstract excerpt
Rabbit Hemorrhagic disease virus (RHDV), a calicivirus of the Lagovirus genus, and responsible for rabbit hemorrhagic disease (RHD), kills rabbits between 48 to 72 hours post infection with mortality rates as high as 50-90%. Caliciviruses, including noroviruses and RHDV, have been shown to bind histo-blood group antigens (HBGA) and human non-secretor individuals lacking ABH antigens in epithelia have been found...
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