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Article

Phosphorylation of VP30 impairs ebola virus transcription.

The Journal of biological chemistry - 6 Sept 2002

Modrof Jens, Mühlberger Elke, Klenk Hans-Dieter, Becker Stephan

Abstract excerpt

Transcription of the highly pathogenic Ebola virus (EBOV) is dependent on VP30, a constituent of the viral nucleocapsid complex. Here we present evidence that phosphorylation of VP30, which takes place at six N-terminal serine residues and one threonine residue, is of functional significance. Replacement of the phosphoserines by alanines resulted in an only slightly phosphorylated VP30 (VP30(6A)) that is still...

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Identifiers

PMID: 12052831
DOI: 10.1074/jbc.M203775200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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