Mosaic AZF deletions and susceptibility to testicular tumors.

Abstract excerpt

We tested for azoospermia factor (AZF) deletions 17 loci corresponding to AZF subintervals a-d in 17 cases of testicular tumors occurring in Finns. While DNA samples from 48 CEPH and 32 Finnish males showed no deletions, patients with testicular cancer displayed AZF deletion mosaicisms in various non-tumor tissues (13 cases) and specific deletion haplotypes in tumor tissues (10 cases). Two of the cases with AZF...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Base Pair Mismatch
• Share to DNA Repair
• Share to Gene Deletion