Article
The envelope glycoprotein of human endogenous retrovirus type W uses a divergent family of amino acid transporters/cell surface receptors.
Journal of virology - 1 Jul 2002
Lavillette Dimitri, Marin Mariana, Ruggieri Alessia, Mallet François, Cosset François-Loïc, Kabat David
Abstract excerpt
The human endogenous retrovirus type W (HERV-W) family includes proviruses with intact protein-coding regions that appear to be under selection pressure, suggesting that some HERV-W proviruses may remain active in higher primates. The envelope glycoprotein (Env) encoded by HERV-W is highly fusogenic, is naturally expressed in human placental syncytiatrophoblasts, and has been reported to function as a...
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