Article
[A linkage disequilibrium study of methylenetetrahydrofolate reductase C677T and schizophrenia].
Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics - 1 Jun 2002
Deng Hong, Liu Xiehe, Cai Guiqing, Sun Xueli, Wang Yingcheng, Terwedow Henry, Wang Zhaoxi, Xu Xin
Abstract excerpt
OBJECTIVE: To explore the relationship between the methylenetetrahy drofolate reductase (MTHFR) C677T missense mutation and schizophrenia by linkage disequilibrium study. METHODS: Linkage disequilibrium analys is was conducted bet ween MTHFR C677T and schizophrenia in 115 affected-sib-pair (105) and trios (10) families by XDT and MAPMAKER/SIBS soft system. The analyses were performed in different diagnostic...
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