Article
Approach of evolutionary theories of ageing, stress, senescence-like phenotypes, calorie restriction and hormesis from the view point of far-from-equilibrium thermodynamics.
Mechanisms of ageing and development - 30 Apr 2002
Toussaint Olivier, Remacle José, Dierick Jean François, Pascal Thierry, Frippiat Christophe, Royer Véronique, Chainiaux Florence
Abstract excerpt
B. L. Strehler wrote that "Any system that is not in thermodynamic equilibrium will approach that state at a rate that is a function of absolute temperature and the energy barriers to the rearrangements of components". Far-from-equilibrium thermodynamics allows a global systemic description of the cellular behaviour. This approach transcends the genetic and stochastic considerations on ageing as well as some...
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