Article
Expression of 25-hydroxyvitamin D-1-alpha-hydroxylase mRNA in individuals with colorectal cancer.
Lancet (London, England) - 25 May 2002
Ogunkolade B W, Boucher B J, Fairclough P D, Hitman G A, Dorudi S, Jenkins P J, Bustin S A
Abstract excerpt
Vitamin D prevents proliferation, promotes differentiation, and induces apoptosis of colon cells, and reduced intake or insufficiency of the vitamin in the body are associated with increased risk of colorectal cancer. Results of previous studies have suggested that mRNA that codes for 25-hydroxyvitamin D-1-alpha-hydroxylase (1 alpha OHase), which converts 25-hydroxyvitamin D to its active metabolite, might be up...
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