Article
[A preliminary genetic reassortment between Hantaan virus and Seoul virus strains].
Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi - 1 Feb 2002
Kang Wenzhen, Huang Changxing, Bai Xuefan, Yang Weisong, Li Guangyu
Abstract excerpt
OBJECTIVE: To determine the frequency and characteristics of reassortment among Hantaan and Seoul viruses causing hemorrhagic fever with renal syndrome (HFRS). METHODS: Mixed infections were initiated in tissue culture, using Hantaan virus strain 76 - 118 and Seoul virus strain SR-11. Potential reassortant virus plaques were picked out by multiplex RT-PCR, using primers specific for individual genome segments (L,...
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