Article
Digital image analysis system for the quantification of infiltrates and cell adhesion molecules in inflammatory cardiomyopathy.
Medical science monitor : international medical journal of experimental and clinical research - 1 May 2002
Noutsias Michel, Pauschinger Matthias, Ostermann Karsten, Escher Felicitas, Blohm Jan-Henrik, Schultheiss Heinz, Kühl Uwe
Abstract excerpt
BACKGROUND: We attempted to develop a digital image analysis (DIA) system for endomyocardial biopsies (EMBs) to reliably quantify a) biopsy quality, b) immunohistochemically-marked infiltrates, and c) cell adhesion molecules (CAMs) in relation to net heart area (HA) for the semi-automated diagnosis of inflammatory cardiomyopathy (InfCM). MATERIAL/METHODS: 140 EMBs from dilated cardiomyopathy (DCM) patients and 14...
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