Article
Quality and quantity of DNA isolated from frozen urine in population-based research.
Analytical biochemistry - 15 May 2002
van der Hel Olga L, van der Luijt Rob B, Bueno de Mesquita H B, van Noord Paul A H, Slothouber Barbara, Roest Mark, van der Schouw Yvonne T, Grobbee Diederick E, Pearson Peter L, Peeters Petra H M
Abstract excerpt
In several population-based studies in the past urine samples were collected and stored for future research. We set out to determine the reliability of using such samples for genotyping DNA markers in epidemiologic research. A source of DNA extracted from exfoliated nucleated cells in urine is provided by the DOM cohort, in which specimens were collected 15-25 years ago. We have examined the quality of the DNA in...
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