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Article

Thioredoxin reductase is essential for the survival of Plasmodium falciparum erythrocytic stages.

The Journal of biological chemistry - 19 Jul 2002

Krnajski Zita, Gilberger Tim-Wolf, Walter Rolf D, Cowman Alan F, Müller Sylke

Abstract excerpt

The human malaria parasite Plasmodium falciparum poses an increasing threat to human health in the tropical regions of the world, and the validation and assessment of possible drug targets is required for the development of new antimalarials. It has been shown that the erythrocytic stages of the parasites, which are responsible for the pathology of the disease in humans, are under enhanced oxidative stress and...

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Identifiers

PMID: 12004069
DOI: 10.1074/jbc.M203539200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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