Article
Fine and ultrafine particles of the diet: influence on the mucosal immune response and association with Crohn's disease.
The Proceedings of the Nutrition Society - 1 Feb 2002
Lomer Miranda C E, Thompson Richard P H, Powell Jonathan J
Abstract excerpt
Crohn's disease is a modern Western disease characterised by transmural inflammation of the gastrointestinal tract. It is of unknown aetiology, but evidence suggests that it results from a combination of genetic predisposition and environmental factors. Bacterial-sized microparticles (0.1-1.0 microm) are potent adjuvants in model antigen-mediated immune responses and are increasingly associated with disease....
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