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Recent Developments on Human Cell Lines for the Bioartificial Liver

1 Mar 2002

Abstract excerpt

Most bioartificial liver (BAL) devices contain porcine primary hepatocytes as their biological component. However, alternatives are needed due to xenotransplantation associated risks. Human liver cell lines have excellent growth characteristics and are therefore candidates for application in BAL devices. Tumour-derived cell lines HepG2 and C3A express a variety of liver functions, but some specific liver...

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PMID: 11999190
DOI: 10.1177/039139880202500304

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