Article
Evaluation of ETF1/eRF1, mapping to 5q31, as a candidate myeloid tumor suppressor gene.
Cancer genetics and cytogenetics - 1 Apr 2002
Dubourg Christèle, Toutain Bertrand, Hélias Catherine, Henry Catherine, Lessard Michel, Le Gall Jean Yves, Le Treut André, Guenet Lucienne
Abstract excerpt
Interstitial deletion of the long arm of chromosome 5 is a recurrent abnormality, mainly associated with myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML), and it has been proposed therefore that the deleted region may contain a myeloid tumor suppressor gene. We have recently mapped a human translation termination factor gene, ETF1, to band 5q31 at D5S500, and thus to the smallest commonly deleted...
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