Article
Platelet glycoprotein Ib alpha receptor polymorphisms and recurrent ischaemic events in acute coronary syndrome patients.
Journal of thrombosis and thrombolysis - 1 Feb 2002
Kenny Dermot, Muckian Clare, Fitzgerald Desmond J, Cannon Christopher P, Shields Denis C
Abstract excerpt
AIMS: To examine the relationship between polymorphisms in the platelet receptor glycoprotein (GP) Ib(alpha) and recurrent ischaemic events, and assess their impact on response to anti-platelet treatment. METHODS AND RESULTS: 1014 patients presenting with unstable coronary syndrome were recruited from the OPUS-TIMI 16 clinical trial of the platelet GPIIb/IIIa antagonist, orbofiban. The subjects were genotyped for...
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