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Genetic study of apolipoprotein E gene, alpha-1 antichymotrypsin gene in sporadic Parkinson disease.

American journal of medical genetics - 8 May 2002

Tang Guomei, Xie Huijun, Xu Lin, Hao Yixin, Lin Dayu, Ren Daming

Abstract excerpt

Several lines of evidence have suggested some common genetic risk factors for Alzheimer disease (AD) and Parkinson disease (PD) because there are some overlapping pathologies in these two neurodegenerative diseases. In the present study, we investigated the role of Apolipoprotein E gene polymorphism and the signal peptide polymorphism in alpha-1 antichymotrypsin (ACT) gene in idiopathic sporadic PD. The study was...

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PMID: 11992569
DOI: 10.1002/ajmg.10249

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