Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of Baicalein on Apoptosis of the Human Hep G2 Cell Line was Induced by Mitochondrial Dysfunction

1 Apr 2002

Abstract excerpt

The effects of baicalein on the human hepatoblastoma G2 (Hep G2) cell line were investigated in this study. By an SRB viability assay, we demonstrated that baicalein reduced the viability in a dose- and time-dependent manner. The apoptotic features such as chromatin condensation and DNA fragmentation were observed in the baicalein-treated cells. During the process of apoptosis, we noticed a sequential dissipation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Flavonoids in Medical Research
Share to Natural product bioactivities and synthesis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 11988851
DOI: 10.1055/s-2002-26760

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of Baicalein on Apoptosis of the Human Hep G2 Cell Line was Induced by Mitochondrial DysfunctionPMID 11988851Read ↗

Apoptosis induced by baicalin involving up-regulation of P53 and bax in MCF-7 cellsSemantic proximity Read ↗

Baicalin-Induced Apoptosis is Mediated by Bcl-2-Dependent, but not p53-Dependent, Pathway in Human Leukemia Cell LinesSemantic proximity Read ↗

Different Effects of Baicalein, Baicalin and Wogonin on Mitochondrial Function, Glutathione Content and Cell Cycle Progression in Human Hepatoma Cell LinesSemantic proximity Read ↗

Cell Death Induced by Baicalein in Human Hepatocellular Carcinoma Cell LinesSemantic proximity Read ↗

Blueberry anthocyanin induces apoptosis in HepG-2 cells and the mechanism of the processSemantic proximity Read ↗

Baicalin Induces Apoptosis of Gallbladder Carcinoma Cells in vitro via a Mitochondrial-Mediated Pathway and Suppresses Tumor Growth in vivoSemantic proximity Read ↗

Baicalein Overcomes Tumor Necrosis Factor–Related Apoptosis-Inducing Ligand Resistance via Two Different Cell-Specific Pathways in Cancer Cells but not in Normal CellsSemantic proximity Read ↗

Antitumor effects of saikosaponins, baicalin and baicalein on human hepatoma cell linesSemantic proximity Read ↗

Melilotus indicus extract induces apoptosis in hepatocellular carcinoma cells via a mechanism involving mitochondria-mediated pathwaysSemantic proximity Read ↗

Baicalein Attenuates Hepatocellular Carcinoma Cell Survival and Induces Apoptosis Through the miR‑3178/HDAC10 pathwaySemantic proximity Read ↗

Scutellaria barbata D. Don induces apoptosis of human colon carcinoma cell through activation of the mitochondrion-dependent pathwaySemantic proximity Read ↗

Baicalein, a Natural Anti-Cancer Compound, Alters MicroRNA Expression Profiles in Bel-7402 Human Hepatocellular Carcinoma CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.