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Different Effects of Baicalein, Baicalin and Wogonin on Mitochondrial Function, Glutathione Content and Cell Cycle Progression in Human Hepatoma Cell Lines

1 Feb 2002

Abstract excerpt

The effects of the flavonoids from Scutellaria baicalensis Georgi (baicalein, baicalin and wogonin) in cultured human hepatoma cells (Hep G2, Hep 3B and SK-Hep1) were compared by MTT assay and flow cytometry. All three flavonoids dose-dependently decreased the cell viabilities accompanying the collapse of mitochondrial membrane potential and the depletion of glutathione content. However, the influence of...

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PMID: 11859462
DOI: 10.1055/s-2002-20246

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