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Article

Two symptomatic cases of dysfibrinogenemia in China: one with gamma-chain Arg275Cys mutation and another without detectable mutation in fibrinogen genes.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jul 2015

Bin Qiong, Liang Fang, Ou Dan-yan, Cui Hai-rong, Luo Jian-ming

Abstract excerpt

The aim of this study was to investigate causative mutations of two unrelated symptomatic Chinese children with dysfibrinogenemia and their family members.Fibrinogen genes, including FGA, FGB and FGG of all participants were PCR-amplified, followed by direct sequencing. Precipitated plasma fibrinogen of some family members was analyzed by western blotting, fibrin polymerization and scanning electron microscopy...

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Source

Identifiers

PMID: 25828970
DOI: 10.1097/MBC.0000000000000290

Genes

FGB
FGG
FGA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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